INTRA-UTERINE TISSUES FROM LATE-PREGNANT RHESUS MONKEYS (MACACA MULATTA) PRODUCE 6-OXO-PROSTAGLANDIN F1α IN VITRO

Abstract
The rates of production of 6-oxo-prostaglandin F (6-oxo-PGF) in vitro by intra-uterine tissues taken from late-pregnant monkeys at Caesarean section have been determined. For tissues obtained between days 140 and 149 of pregnancy (late pregnancy) the general quantitative order of rates of production (per unit weight) was decidua basalis> placenta > decidua parietalis>amnion>chorion = myometrium. When tissues were taken between days 160 and 168 of pregnancy (near term) this order was placenta > decidua parietalis = amnion> myometrium = decidua basalis > chorion. There was a significant reduction near term in the rate of production of 6-oxo-PGF by decidua basalis; all other tissues exhibited similar rates of production at the two gestational periods investigated.