Alterations in Rat Serum Proteins in Folic Acid and Vit. B12 Deficiency.

Abstract
1. In a deficiency of vit. B12 and folic acid in rats, there is a significant reduction in total serum proteins and in serum albumin, α1-globulin and γ-globulin. An increase in the proportion of β-globulin is probably indicative of higher serum level of free vit. B12 in the deficient state. 2. Dietary protein level influences serum concentrations of albumin, α1-globulin and, to a lesser extent, γ-globulin.