Identification of multiple sources of charge heterogeneity in a recombinant antibody
Top Cited Papers
- 20 February 2001
- journal article
- Published by Elsevier in Journal of Chromatography B: Biomedical Sciences and Applications
- Vol. 752 (2) , 233-245
- https://doi.org/10.1016/s0378-4347(00)00548-x
Abstract
No abstract availableThis publication has 30 references indexed in Scilit:
- Herceptin®: Breaking New GroundCancer Biotherapy & Radiopharmaceuticals, 1999
- Isomerization of an Aspartic Acid Residue in the Complementarity-Determining Regions of a Recombinant Antibody to Human IgE: Identification and Effect on Binding AffinityBiochemistry, 1996
- An Integrated Strategy for Structural Characterization of the Protein and Carbohydrate Components of Monoclonal Antibodies: Application to Anti-Respiratory Syncytial Virus MAbAnalytical Chemistry, 1995
- Isolation and Characterization of 101-Succinimide Lysozyme That Possesses the Cyclic Imide at Asp101-Gly102Biochemistry, 1994
- Identification of succinimide sites in proteins by N‐terminal sequence analysis after alkaline hydroxylamine cleavageProtein Science, 1994
- X-ray Structures of the Antigen-binding Domains from Three Variants of Humanized anti-p185HER2 Antibody 4D5 and Comparison with Molecular ModelingJournal of Molecular Biology, 1993
- Sequence-specific deamidation: isolation and biochemical characterization of succinimide intermediates of recombinant hirudinBiochemistry, 1993
- Isolation and characterization of porcine somatotropin containing a succinimide residue in place of aspartate129Protein Science, 1992
- Antigen binding thermodynamics and antiproliferative effects of chimeric and humanized anti-p185HER2 antibody Fab fragmentsBiochemistry, 1992
- Comparative structural study of the N-linked oligosaccharides of human normal and pathological immunoglobulin GBiochemistry, 1987