Development of the new potent non-peptide gpIIb/IIIa antagonist NSL-95301 by utilizing combinatorial technique
- 21 January 1997
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 7 (2) , 209-212
- https://doi.org/10.1016/s0960-894x(96)00610-5
Abstract
No abstract availableKeywords
This publication has 17 references indexed in Scilit:
- Integrin adhesion receptors: structure, function and implications for biomedicineMolecular Medicine Today, 1996
- Design and synthesis of new antagonist peptides for platelet GPIIb/IIIa receptor as anti-thrombotic agentsBioorganic & Medicinal Chemistry Letters, 1996
- Novel antiplatelet therapies for treatment of patients with ischemic heart disease: Inhibitors of the platelet glycoprotein IIbIIIa integrin receptorAmerican Heart Journal, 1995
- Design, synthesis and SAR of RGD peptide hybrids as highly efficient inhibitors of platelet aggregationBioorganic & Medicinal Chemistry Letters, 1995
- Structure-activity relationships of double-strand RGD peptides as GPIIb/IIIa receptor antogonistsBioorganic & Medicinal Chemistry Letters, 1994
- Platelets and Thrombolytic TherapyNew England Journal of Medicine, 1990
- New Perspectives in Cell Adhesion: RGD and IntegrinsScience, 1987
- Unstable angina with fatal outcome: dynamic coronary thrombosis leading to infarction and/or sudden death. Autopsy evidence of recurrent mural thrombosis with peripheral embolization culminating in total vascular occlusion.Circulation, 1985
- Dualistic nature of adhesive protein function: fibronectin and its biologically active peptide fragments can autoinhibit fibronectin function.The Journal of cell biology, 1984
- Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the moleculeNature, 1984