Thalidomide: Effects on Ehrlich Ascites Tumor Cells in vitro
- 26 June 1964
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 144 (3626) , 1583
- https://doi.org/10.1126/science.144.3626.1583
Abstract
Thalidomide did not inhibit dehydrogenase activity or growth of Ehrlich ascites tumor cells in agar. When mixed with Ehrlich ascites tumor cells in vitro, thalidomide increased the mitotic activity. The effect of the thalidomide was not altered by the addition of nicotinic or folic acid, or by vitamin B1 or B6. Oxygen uptake by the tumor cells was not affected by thalidomide.Keywords
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