Nucleosome reconstitution of core-length poly(dG.cntdot.poly(dC) and poly(rG-dC).cntdot.poly(rG-dC)
- 7 February 1989
- journal article
- research article
- Published by American Chemical Society (ACS) in Biochemistry
- Vol. 28 (3) , 975-980
- https://doi.org/10.1021/bi00429a009
Abstract
The double-stranded polyurine.cntdot.polypyridimidines poly(dG).cntdot.poly(dC) and poly[d(A-G)].cntdot.poly[d(T-C)]] and the mixed ribose-deoxyribose polynucleotdie poly(rG-dC).cntdot.poly(rG-dC) have been successfully reconstitued into nucleosomes. The radioactively labeled particles comigrate in gel electrophoresis and sucrose density gradient experiments with authentic nucleosomes derived from chicken erythrocyte chromatin. These results show that nucleosomes are able to accommodate a wider variety of polynucleotides than was previously believed.This publication has 0 references indexed in Scilit: