Alterations in Gastrointestinal Microflora During Antimicrobial Therapy for Necrotizing Enterocolitis
- 1 March 1979
- journal article
- research article
- Published by American Academy of Pediatrics (AAP) in Pediatrics
- Vol. 63 (3) , 425-428
- https://doi.org/10.1542/peds.63.3.425
Abstract
Changes in the gastrointestinal microflora were noted in 22 infants during comlbined topical and parenteral antimicrobial therapy for necrotizing enterocolitis (NEC). Gastric and fecal cultures obtained during therapy showed significantly decreased Gram-negative aerobic organisms, most of which were Enterobacteriaceae, when compared with pretreatment cultures. Members of this bacterial family have been implicated in the pathogenesis of NEC in many reports. The data presented here show that the number of organisms retrieved can be reduced with this method of antimicrobial therapy.Keywords
This publication has 1 reference indexed in Scilit:
- Clindamycin-Associated ColitisAnnals of Internal Medicine, 1974