A previously described serum protein polymorphism in the rat identified as Gc (‘vitamin D-binding protein’)

Abstract
The previously published serum protein polymorphisms Gl-1 [.alpha.-globulin] and tf [transferrin] are identical and represent genetic variation at the locus of the vitamin D-binding .alpha.-globulin, also known as Gc or group-specific component. The identity was established by comparative protein staining, by functional tests with 14C-vitamin D3, by immunological studies with specific anti-Gc sera and by the strain distribution patterns. The Gc polymorphism in the rat [Rattus norvegicus] may initiate interesting physiological and genetical studies.