mbs: modifying Hudson's ms software to generate samples of DNA sequences with a biallelic site under selection
Open Access
- 30 May 2009
- journal article
- Published by Springer Nature in BMC Bioinformatics
- Vol. 10 (1) , 166
- https://doi.org/10.1186/1471-2105-10-166
Abstract
The pattern of single nucleotide polymorphisms, or SNPs, contains a tremendous amount of information with respect to the mechanisms of the micro-evolutionary process of a species. The inference of the roles of these mechanisms, including natural selection, relies heavily on computer simulations. A coalescent simulation is extremely powerful in generating a large number of samples of DNA sequences from a population (species) when all mutations are neutral, and Hudson's ms software is frequently used for this purpose.Keywords
This publication has 6 references indexed in Scilit:
- Recent and ongoing selection in the human genomeNature Reviews Genetics, 2007
- How reliable are empirical genomic scans for selective sweeps?Genome Research, 2006
- Faculty Opinions recommendation of Detecting a local signature of genetic hitchhiking along a recombining chromosome.Published by H1 Connect ,2002
- Generating samples under a Wright–Fisher neutral model of genetic variationBioinformatics, 2002