The pathophysiology of extrapyramidal side-effects of neuroleptic drugs
- 1 February 1980
- journal article
- research article
- Published by Cambridge University Press (CUP) in Psychological Medicine
- Vol. 10 (1) , 55-72
- https://doi.org/10.1017/s003329170003960x
Abstract
SYNOPSIS: The mechanisms responsible for the production of major extrapyramidal side-effects (parkinsonism, akathisia, acute dystonic reactions, chronic tardive dyskinesias) are reviewed in the light of the complex effects of these drugs on cerebral dopamine systems.Keywords
This publication has 98 references indexed in Scilit:
- Modification of Tardive Dyskinesia and Spasmodic Torticollis by ApomorphineArchives of Neurology, 1978
- Pharmacokinetics of Red Blood Cell Phenothiazine and Clinical EffectsArchives of General Psychiatry, 1976
- Excitation-mediating and inhibition-mediating dopamine-receptors: A new concept towards a better understanding of electrophysiological, biochemical, pharmacological, functional and clinical dataPsychopharmacology, 1976
- Drug and Sociotherapy in the Aftercare of Schizophrenic PatientsArchives of General Psychiatry, 1974
- Dopaminergic hypersensitivity and cholinergic hypofunction in the pathophysiology of tardive dyskinesiaPsychopharmacology, 1974
- Physiologic and clinical effects of chlorpromazine and their relationship to plasma levelClinical Pharmacology & Therapeutics, 1972
- Treatment of Tardive DyskinesiaArchives of General Psychiatry, 1972
- Treatment of Tardive DyskinesiaArchives of General Psychiatry, 1972
- Phenothiazine Treatment in Acute SchizophreniaArchives of General Psychiatry, 1964
- A Survey of Drug-Induced Extrapyramidal ReactionsJAMA, 1961