Cardiac Stroke Volume as a Determinant of Influenzal Fatality

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Abstract
Epidemiology and PathologyAS the lethal activities of man decreased in the closing months of World War I, a new lethal agent emerged that killed 20 million people around the world.1 The disease was pandemic influenza, and the agent a new influenza virus.2 In Ireland the average endemic mortality rate from influenza from 1901 through 1917 was 29 per 100,000 per year for males. The epidemics of 1892, 1900 and 1918 had mortality rates of 81, 105 and 243 respectively. The 1918 rate was highest, but much more striking was the change in age distribution of those dying. Although the . . .