Lack of Evidence for Neurogenic Renal Vasodilatation in Anesthetized Dogs

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Abstract
Carotid baroreceptor reflex induced decreases in renal sympathetic nerve activity result in only minimal renal vasodilatation which was unaffected by renal cholinergic blockade with atropine. Renal cholinergic blockade with atropine did not diminish the renal vasodilation responses to decreases in renal perfusion pressure. Renal adrenergic blockade did not unmask a renal vasodilator response to direct electrical renal nerve stimulation. The neurogenic contribution to renal vasodilatation was small in comparison to the neurogenic contribution to renal vasoconstriction. Evidence for participation of renal cholinergic neural pathways in renal vasodilatation was not found.