Ongoing Control of Haemophilus influenzae Type B Infections in Canadian Children, 2004–2007

Abstract
The uniform use in Canada of a single Haemophilus influenzae type b conjugate vaccine in combination with diphtheria, tetanus, acellular pertussis, and inactivated poliovirus vaccines (DTaP.IPV/Hib) facilitates ongoing assessment of vaccine effectiveness, including any effects of recently added concurrent vaccinations and increasing time since vaccination. Surveillance at 12 pediatric centers in 2004–2007 indicates that vaccine failures remain rare and case totals approach an irreducible minimum, with no age shift.