Human sperm chromosomes
- 1 February 1988
- journal article
- research article
- Published by Oxford University Press (OUP) in Human Reproduction
- Vol. 3 (2) , 133-138
- https://doi.org/10.1093/oxfordjournals.humrep.a136662
Abstract
Sperm chromosome studies have been performed in 70 nor–mal males. The incidence of aneuploidy in this group is ∽ 3−4%, and that of structural anomalies close to 5%. In carriers of reciprocal or Robertsonian translocations, the results are extremely variable, with percentages of unbalanced sperm from 8 to 87÷. No unbalanced spermatozoa have been observed in patients with pericentric or paracentric inver–sions. In cancer patients treated with radio and/or chemotherapy, the incidence of chromosome abnormalities is much higher, and significantly different from that found in controls.Keywords
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