Analysis of Proteins of the Stria Vascularis of the Normal and the Waltzing Guinea Pig
- 1 January 1980
- journal article
- research article
- Published by Taylor & Francis in Acta Oto-Laryngologica
- Vol. 90 (1-6) , 66-73
- https://doi.org/10.3109/00016488009131699
Abstract
Proteins of the stria vascularis of the normal and the genetically deaf waltzing guinea pig were analysed by one and two-dimensional acrylamide gel electrophoresis. Cochlear proteins were labeled in vivo by replacing the perilymph with a solution containing radioactive precursors. With the two-dimensional analysis. more than 200 polypeptides were resolved. Proteins that are exposed on the endolymphatic surface of the stria vascularis were identified by lactoperoxidase-catalysed iodination. Seven polypeptides were identified with this technique. No consistent changes in protein patterns of the stria vascularis from the waltzing guinea pig were detected.This publication has 22 references indexed in Scilit:
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