Studies of the association of the A, B and Lewis Blood group antigens with carcinoembryonic antigen (CEA).
- 1 April 1974
- journal article
- Vol. 26 (4) , 831-43
Abstract
Carcinoembryonic antigen (CEA) was purified from primary tumour or from hepatic metastases obtained from ten cases of carcinoma of the colon. In nine cases the blood group antigens A, B, Lea or Leb were detected in CEA preparations by the binding of 125I-labelled CEA by blood group antibodies. The extent of binding appeared to preclude simple contamination of CEA preparations by blood group glycoprotein. In all cases the blood group antigens detected were consistent with the patients' known blood groups. Blood group I and i activities were not detected.This publication has 30 references indexed in Scilit:
- Carcinoembryonic Antigen (CEA) in non digestive cancerous and normal tissuesImmunochemistry, 1973
- Carcinoembryonic antigen (CEA): Demonstration of a partial identify between CEA and a normal glycoproteinImmunochemistry, 1972
- STRUCTURAL STUDIES OF THE MAJOR GLYCOPROTEIN IN PREPARATIONS WITH CARCINOEMBRYONIC ANTIGEN ACTIVITYThe Journal of Experimental Medicine, 1972
- The preparation of purified carcinoembryonic antigen of the human digestive system from large quantities of tumor tissueImmunochemistry, 1972
- Absence of circulating antibodies to carcinoembryonic antigen in patients with gastrointestinal malignanciesInternational Journal of Cancer, 1972
- Demonstration of antigens related to colonic cancer in the human digestive systemInternational Journal of Cancer, 1970
- Glycosphingolipids with Lewis Blood Group Activity: Uptake by Human ErythrocytesScience, 1969
- PHYSICOCHEMICAL STUDIES OF THE CARCINOEMBRYONIC ANTIGENS OF THE HUMAN DIGESTIVE SYSTEMThe Journal of Experimental Medicine, 1968
- Studies of Blood Group SubstancesTransfusion, 1967
- Possible Genetical Pathways for the Biosynthesis of Blood Group MucopolysaccharidesVox Sanguinis, 1959