Satellite DNA in Constitutive Heterochromatin of the Guinea Pig
- 10 April 1970
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 168 (3928) , 263-265
- https://doi.org/10.1126/science.168.3928.263
Abstract
Total DNA and DNA from the heterochromatin and euchromatin fractions of male guinea pig liver nuclei were analyzed by cesium sulfate-silver density-gradient centrifugation. Total DNA is composed of three components: a heavy satellite DNA, a main DNA of intermediate density, and a light satellite DNA. Heterochromatin DNA shows a fourfold enrichment in the satellite components while euchromatin DNA is relatively devoid of them. The strands of both satellite DNA's are separable by centrifugation in alkaline cesium chloride. Base analyses on the separate strands demonstrate that the two satellite DNA's represent different species.Keywords
This publication has 12 references indexed in Scilit:
- Constitutive heterochromatin during early embryogenesis of Microtus agrestisExperimental Cell Research, 1970
- Localization of mouse satellite DNA in constitutive heterochromatinExperimental Cell Research, 1970
- Gene Regulation for Higher Cells: A TheoryScience, 1969
- Satellite DNA in mouse autosomal hetero chromatinBiochemical and Biophysical Research Communications, 1969
- Some properties of the single strands isolated from the DNA of the nuclear satellite of the mouse (Mus musculus)Journal of Molecular Biology, 1969
- The Nucleolus in Cell MetabolismAnnual Review of Plant Physiology, 1967
- HeterochromatinScience, 1966
- Spectrophotometric, potentiometric, and density gradient ultracentrifugation studies of the binding of silver ion by DNABiopolymers, 1966
- Interphase Deoxyribonucleic Acid Condensation, Late Deoxyribonucleic Acid Replication, and Gene InactivationNature, 1965
- A procedure for the isolation of deoxyribonucleic acid from micro-organismsJournal of Molecular Biology, 1961