Pyridoxine for Neonatal Seizures: an Unexpected Danger
- 1 June 1985
- journal article
- case report
- Published by Wiley in Developmental Medicine and Child Neurology
- Vol. 27 (3) , 377-379
- https://doi.org/10.1111/j.1469-8749.1985.tb04551.x
Abstract
A case of pyridoxine-dependent seizures is reported. Administration of pyridoxine to an infant after a long period of convulsions was followed by acute hypotonia. Other cases have been reported in the literature, in one of which assisted ventilation was required. A possible mechanism for this alarming outcome is discussed, and it is suggested that resuscitation facilities should be quickly available during such trials.Keywords
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