OSTEOGENETIC ACTIVITY OF TRANSPLANTED TRANSITIONAL EPITHELIUM

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Abstract
Osteogenetic activity of transitional epithelium in transplants occurs when infiltrative growth of the epithelium takes place and the epithelial cells have the ability to enter the connective tissue. By their morphological and histochemical characteristics, the parts of the transitional epithelium which are responsible for osteogenetic induction are in a state of incomplete differentiation corresponding to the intermediate layer cells. In guinea-pigs, the osteogenetic activity of transitional epithelium is invariably accompanied by secretion of glycogen-like polysaccharides from the epithelium into the underlying tissue. Some possible explanations of the osteogenetic activity of transitional epithelium are discussed from the point of view of the similarity of this tissue and the epithelium of the kidney collecting tubules.

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