Promoter Hypermethylation--Can This Change Alone Ever Designate True Tumor Suppressor Gene Function?

This publication has 11 references indexed in Scilit:

• Epigenetic Inactivation of RASSF1A in Lung and Breast Cancers and Malignant Phenotype Suppression
  JNCI Journal of the National Cancer Institute, 2001
• Aberrant Methylation of Gene Promoters in Cancer--Concepts, Misconcepts, and Promise
  JNCI Journal of the National Cancer Institute, 2000
• Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3
  Nature Genetics, 2000
• DNA hypermethylation in tumorigenesis: epigenetics joins genetics
  Trends in Genetics, 2000
• Mice deficient in the candidate tumor suppressor gene Hic1 exhibit developmental defects of structures affected in the Miller-Dieker syndrome
  Human Molecular Genetics, 2000
• Aberrant CpG-island methylation has non-random and tumour-type–specific patterns
  Nature Genetics, 2000
• CpG island methylator phenotype in colorectal cancer
  Proceedings of the National Academy of Sciences, 1999
• Hypermethylation of the DAP-Kinase CpG Island Is a Common Alteration in B-Cell Malignancies
  Blood, 1999
• Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
  Proceedings of the National Academy of Sciences, 1998
• p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3
  Nature Medicine, 1995