Experimental infection of mice with Madurella mycetomi

Abstract
Following Borelli's (1957) observations, the production of granulomata and typical grains by Madurella mycetomi in peritoneal structures of the white mouse has been studied. Most regular grain production follows intraperitoneal injection of a mixture of 4 mg. or more of M. mycetoma, strain L20, and 4 mg. or more of killed Mycobacterium tuberculosis. Grains are also produced, but less regularly, by multiple intraperitoneal injections of the fungus alone.

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