Detection of HIV-1 Genome in Leukocytes of Human Colostrum from Anti-HIV-1 Seropositive Mothers
- 1 July 1992
- journal article
- research article
- Published by Mary Ann Liebert Inc in AIDS Research and Human Retroviruses
- Vol. 8 (7) , 1283-1287
- https://doi.org/10.1089/aid.1992.8.1283
Abstract
In order to obtain more information about the presence of HIV-1 in mononuclear cells of colostrum, research was carried out on both the HIV-1 genome in the cellular fraction of colostrum and the viral antibody in cell-free colostrum of eight anti-HIV-1 seropositive asymptomatic mothers. In five cases cell fractions of the colostrum harbored HIV-1 genome by DNA-DNA and DNA-RNA in situ hybridization, whereas viral antibody were detected in all cell-free colostrum specimens. The data confirms the colostrum as a possible route of HIV-1 infection.Keywords
This publication has 15 references indexed in Scilit:
- HIV viral sequences in seronegative people at risk detected by in situ hybridisation and polymerase chain reaction.BMJ, 1989
- BREASTFEEDING AND TRANSMISSION OF HIVThe Lancet, 1988
- HIV INFECTION, BREASTFEEDING, AND HUMAN MILK BANKINGThe Lancet, 1988
- Transmission of the Human Immunodeficiency VirusNew England Journal of Medicine, 1987
- AIDS AND HUMAN MILK BANK CLOSURESThe Lancet, 1987
- INFANTS BORN TO MOTHERS SEROPOSITIVE FOR HUMAN IMMUNODEFICIENCY VIRUSThe Lancet, 1987
- ISOLATION OF AIDS VIRUS FROM CELL-FREE BREAST MILK OF THREE HEALTHY VIRUS CARRIERSThe Lancet, 1985
- POSTNATAL TRANSMISSION OF AIDS-ASSOCIATED RETROVIRUS FROM MOTHER TO INFANTThe Lancet, 1985
- Molecular Characterization of Human T-Cell Leukemia (Lymphotropic) Virus Type III in the Acquired Immune Deficiency SyndromeScience, 1984
- Molecular cloning and characterization of the HTLV-III virus associated with AIDSNature, 1984