Synthesis and reactions of 4,6‐dimethoxyindole, an unusual indole system
- 1 August 1969
- journal article
- research article
- Published by Wiley in Journal of Heterocyclic Chemistry
- Vol. 6 (4) , 539-543
- https://doi.org/10.1002/jhet.5570060414
Abstract
A synthesis of 4,6‐dimethoxyindole is described. Formylation or oxalylation reactions gave substitution at position 7 rather than the usual 3‐substitution characteristic of other indoles. A synthesis of N,N‐dimethyl‐4,6‐dimethoxytryptamine is presented along with NMR data for 3 and 7‐substituted compounds in this series.Keywords
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