Ophthalmopathy of Graves' Disease

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Abstract
Soft-tissue swelling that would be innocuous in many locations has serious effects where local anatomy confines the swelling tissues within an inexpansible space. The anterior-tibial-compartment and carpal-tunnel syndromes are good examples of such conditions. The severe ophthalmopathy of Graves' disease is another.The orbit may be thought of as a bony cup open only to the front, where its orifice is occluded by the eye. The space behind the eye is occupied mostly by extraocular muscles and fat. Through it run arteries, veins, and the optic nerve.In Graves' disease a still unidentified pathogen or its mediator induces swelling, lymphocytic . . .