MICROBIOLOGICAL STUDIES ON THE MECHANISM OF ACTION OF SPARSOMYCIN
- 1 August 1966
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Microbiology
- Vol. 12 (4) , 595-604
- https://doi.org/10.1139/m66-085
Abstract
A primary site of sparsomycin attack in Escherichia coli appears to be inhibition of synthesis of protein, which occurs at concentrations of sparsomycin that do not affect DNA or RNA synthesis. Sparsomycin interferes with the normal excretion of amino acids by E. coli. Some cross-resistance was observed between a culture resistant to sparsomycin and cultures resistant to other inhibitors of protein synthesis.This publication has 17 references indexed in Scilit:
- THE EFFECT OF ACTINOBOLIN ON NUCLEIC ACID AND PROTEIN SYNTHESIS IN ESCHERICHIA COLICanadian Journal of Microbiology, 1966
- Sparsomycin Modification of the Lethal Action of Ionizing Irradiation on Escherichia coliNature, 1965
- A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acidBiochemical Journal, 1956
- The assimilation of amino-acids by bacteria. 15. Actions of antibiotics on nucleic acid and protein synthesis in Staphylococcus aureusBiochemical Journal, 1953
- Medium for Assay of Vitamins with Lactic Acid BacteriaAnalytical Chemistry, 1951
- The Path of Carbon in Photosynthesis. V. Paper Chromatography and Radioautography of the Products1Journal of the American Chemical Society, 1950
- The Relative Errors of Bacteriological Plate Counting MethodsJournal of Bacteriology, 1947
- Über die Bestimmung kleiner Pentosemengen, insbesondere in Derivaten der AdenylsäureHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1939