Effect of tissue transglutaminase on the solubility of proteins containing expanded polyglutamine repeats
Open Access
- 4 February 2004
- journal article
- research article
- Published by Wiley in Journal of Neurochemistry
- Vol. 88 (5) , 1253-1260
- https://doi.org/10.1046/j.1471-4159.2003.02249.x
Abstract
The expansion of a polyglutamine (polyQ) domain in neuronal proteins is the molecular genetic cause of at least eight neurodegenerative diseases. Proteins with a polyQ domain that is greater than 40 ...Keywords
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