Ocular Hypertensive Responses in Pigmented Rabbits Following Different Methods of Waterloading
- 1 January 1986
- journal article
- research article
- Published by Mary Ann Liebert Inc in Journal of Ocular Pharmacology and Therapeutics
- Vol. 2 (4) , 313-317
- https://doi.org/10.1089/jop.1986.2.313
Abstract
Waterloading tests are used in rabbits to screen potentially useful ocular hypotensive drugs. The present study examines the ocular hypertensive response following oral, intravenous and intraperitoneal administration of water in conscious Dutch belt pigmented rabbits. All methods of waterloading were well tolerated by rabbits. However, intraperitoneal waterloading provided an ocular hypertensive effect of longer duration than either oral or intravenous waterloading.Keywords
This publication has 7 references indexed in Scilit:
- Local Ocular Hypotensive Effect of Topically Applied AcetazolamideAmerican Journal of Ophthalmology, 1984
- The effect of hypotensive drugs on the intraocular pressure after waterloading in rabbitsDocumenta Ophthalmologica, 1981
- Adrenergic drugs and intraocular pressure: Suppression of ocular hypertension induced by water loadingExperimental Eye Research, 1980
- Provocative tests and chronic simple glaucoma. I. Effect of atropine on the water-drinking test: intimations of central regulatory control. II. Fluorescein angiography provocative test: a new approach to separation of the normal from the pathological.British Journal of Ophthalmology, 1972
- The Water-Loading Test in RabbitsArchives of Ophthalmology (1950), 1969
- A Tonographic Study of Water Loading in RabbitsArchives of Ophthalmology (1950), 1967
- The Water Provocative Test in Glaucomatous Patients* *From the Department of Surgery (Ophthalmology) of the New York Hospital-Cornell Medical Center. This study was aided in part by grants from the National Society for the Prevention of Blindness and the National Council to Combat Blindness.American Journal of Ophthalmology, 1961