Incorporation of in vitro enzyme data into the physiologically-based pharmacokinetic (PB-PK) model for methylene chloride: implications for risk assessment
- 31 October 1988
- journal article
- Published by Elsevier in Toxicology Letters
- Vol. 43 (1-3) , 97-116
- https://doi.org/10.1016/0378-4274(88)90023-9
Abstract
No abstract availableKeywords
This publication has 6 references indexed in Scilit:
- Physiologically based pharmacokinetics and the risk assessment process for methylene chlorideToxicology and Applied Pharmacology, 1987
- Oxidation of 4-aryl- and 4-alkyl-substituted 2,6-dimethyl-3,5-bis(alkoxycarbonyl)-1,4-dihydropyridines by human liver microsomes and immunochemical evidence for the involvement of a form of cytochrome P-450Journal of Medicinal Chemistry, 1986
- Metabolism of inhaled dihalomethanes in vivo: Differentiation of kinetic constants for two independent pathwaysToxicology and Applied Pharmacology, 1986
- Methylene chloride: A two-year inhalation toxicity and oncogenicity study in rats and hamsters*1Fundamental and Applied Toxicology, 1984
- STRUCTURE AND QUANTIFICATION OF A PHYSIOLOGICAL MODEL OF THE DISTRIBUTION OF INJECTED AGENTS AND INHALED ANAESTHETICSBritish Journal of Anaesthesia, 1981
- The Determination of Enzyme Dissociation ConstantsJournal of the American Chemical Society, 1934