Inhibition of Proline Utilization by Glutamate during Steady-state Growth of Saccharomyces cerevisiae
- 1 November 1977
- journal article
- research article
- Published by Microbiology Society in Journal of General Microbiology
- Vol. 103 (1) , 123-126
- https://doi.org/10.1099/00221287-103-1-123
Abstract
Proline utilization during growth of S. cerevisiae is inhibited by the presence of other amino acids. Steady-state simultaneous utilization of proline and glutamate is possible in a N-limited continuous culture. A switch of steady-state inhibition of proline utilization may be effected by a change in growth rate. Under the conditions studied, inhibition occurred on the catabolic route from proline to glutamate and was not mediated through the concentration of pool amino acids. In batch culture, the control site was shifted to proline permease by increasing the extracellular concentration of glutamate.This publication has 2 references indexed in Scilit:
- AN IMPROVED COLORIMETRIC METHOD FOR THE DETERMINATION OF PROLINE IN THE PRESENCE OF OTHER NINHYDRIN-POSITIVE COMPOUNDSBiochemical Journal, 1965
- ABSORPTION OF AMINO ACIDS FROM WORT BY YEASTSJournal of the Institute of Brewing, 1964