Molecular characterization and distribution of motilin family receptors in the human gastrointestinal tract
- 28 April 2006
- journal article
- research article
- Published by Springer Nature in The Esophagus
- Vol. 41 (3) , 223-230
- https://doi.org/10.1007/s00535-005-1739-0
Abstract
Motilin and ghrelin have been recognized as important endogenous regulators of gastrointestinal motor function in mammals, mediated respectively by the motilin receptor and by the closely related ghrelin receptor. The aims of this study were to explore the distribution of motilin and ghrelin receptors along the human gastrointestinal tract and to establish the molecular nature of the human motilin receptor.Keywords
This publication has 42 references indexed in Scilit:
- Demonstration of a Specific Site of Covalent Labeling of the Human Motilin Receptor Using a Biologically Active Photolabile Motilin AnalogThe Journal of Pharmacology and Experimental Therapeutics, 2005
- Ghrelin Induces Fasted Motor Activity of the Gastrointestinal Tract in Conscious Fed RatsThe Journal of Physiology, 2003
- Differential Determinants for Peptide and Non-peptidyl Ligand Binding to the Motilin ReceptorJournal of Biological Chemistry, 2002
- Multiple Extracellular Loop Domains Contribute Critical Determinants for Agonist Binding and Activation of the Secretin ReceptorJournal of Biological Chemistry, 1996
- Effect of oral erythromycin on colonic transit in patients with idiopathic constipation a pilot studyDigestive Diseases and Sciences, 1995
- Immunocytochemical localization of motilin-containing cells in the rabbit gastrointestinal tractPeptides, 1995
- Oral or intravenous erythromycin has no effect on human distal colonic motilityAlimentary Pharmacology & Therapeutics, 1992
- N-Terminal portion of motilin determines its biological activityBiochemical and Biophysical Research Communications, 1992
- Erythromycin and its derivatives with motilin-like biological activities inhibit the specific binding of 125I-motilin to duodenal muscleBiochemical and Biophysical Research Communications, 1988
- Sites and mechanisms of action of neuropeptides on canine gastric motility differ andLife Sciences, 1983