2-ethyl-5-(3-indolyl)oxazole from Streptomyces cinnamomeus discovered by chemical screening. Characterization and structure elucidation by X-ray analysis.
- 1 January 1982
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 35 (5) , 549-555
- https://doi.org/10.7164/antibiotics.35.549
Abstract
In the lipophilic extracts from S. cinnamomeus, 2-ethyl-5-(3-indolyl)oxazole (1a) was detected by chemical screening methods. The structure of the crystalline 1a was determined by spectroscopic and X-ray analysis. The new mono- and dibromo derivatives 1b and 1c are described. 1a is identical with pimprinethine and belongs to a group of microbial indole alkaloids, which can be regarded as masked tryptamine derivatives.This publication has 3 references indexed in Scilit:
- Stoffwechselprodukte von Mikroorganismen. 193. Mitteilung. FerrithiocinHelvetica Chimica Acta, 1980
- Identification of mycolutein and pulvomycin as aureothin and labilomycin respectively.The Journal of Antibiotics, 1976
- The structure and synthesis of pimprinineTetrahedron, 1963