Abstract
Soluble extracts of M. capsulatus (Bath), obtained by centrifugation of crude extracts at 160,000 g for 1 h, catalyze the NAD(P)H- and O2-dependent disappearance of bromomethane and also the formation of methanol from methane. Soluble methane mono-oxygenase is not inhibited by chelating agents or by most electron-transport inhibitors and is a multicomponent enzyme.