Lipase‐Catalyzed acyiation of sugars solubilized in hydrophobic solvents by complexation
Open Access
- 5 September 1993
- journal article
- review article
- Published by Wiley in Biotechnology & Bioengineering
- Vol. 42 (6) , 788-791
- https://doi.org/10.1002/bit.260420616
Abstract
By complexing glucose and other mono- and disaccharides with phenylboronic acid, they were solubilized in many organic solvents. Pseudomonas sp. lipoprotein lipase readily acylated such solubilized sugars in these solvents (no reaction was observed without phenylboronic acid, i.e., when sugars are insoluble in the reaction medium). Solubilized D-glucose was enzymatically acylated with vinyl acrylate on a preparative scale, and the resultant 6-O-acryloylglucose was chemically polymerized to yield a sugar-based polyacrylate with a molecular weight of 14,000 Da. © 1993 John Wiley & Sons, Inc.Keywords
This publication has 19 references indexed in Scilit:
- Sugar solubilization agent for enzymatic condensation of glucose in organic solventsBiotechnology Letters, 1992
- Enzymatic and chemoenzymatic approaches to polymer synthesisTrends in Biotechnology, 1992
- Chemoenzymatic synthesis of novel sucrose-containing polymersMacromolecules, 1991
- Enzymatic synthesis of a sucrose‐containing linear polyester in nearly anhydrous organic mediaBiotechnology & Bioengineering, 1991
- Enzymes in carbohydrate synthesis. Lipase-catalyzed selective acylation and deacylation of furanose and pyranose derivativesThe Journal of Organic Chemistry, 1988
- Lipase-catalyzed irreversible transesterifications using enol esters as acylating reagents: preparative enantio- and regioselective syntheses of alcohols, glycerol derivatives, sugars and organometallicsJournal of the American Chemical Society, 1988
- Production of biosurfactants from sugar alcohols and vegetable oils catalyzed by lipases in a nonaqueous mediumBiotechnology & Bioengineering, 1988
- Protease-catalyzed regioselective esterification of sugars and related compounds in anhydrous dimethylformamideJournal of the American Chemical Society, 1988
- Regioselective acylation of secondary hydroxyl groups in sugars catalyzed by lipases in organic solventsJournal of the American Chemical Society, 1987
- 13C-nuclear magnetic resonance (NMR) spectra of O-acylglucoses. Additivity of shift parameters and its application to structure elucidations.CHEMICAL & PHARMACEUTICAL BULLETIN, 1980