Pharmacological Modulation by Cetirizine and Ebastine of the Cutaneous Reactivity to Histamine
- 1 January 1991
- journal article
- clinical trial
- Published by S. Karger AG in Dermatology
- Vol. 183 (3) , 208-211
- https://doi.org/10.1159/000247671
Abstract
The peripheral H1-inhibiting effects of cetirizine 10 mg and ebastine 10 mg were compared at the skin level after single oral administration. The study was performed in 9 healthy subjects under double-blind randomized crossover conditions. Both drugs were significantly effective up to 24 h. The suppressive effect of cetirizine was significantly more rapid and more marked.Keywords
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