Agglutination of Bacteria by Hemoglobin
- 1 December 1957
- journal article
- research article
- Published by Taylor & Francis in Acta Rheumatologica Scandinavica
- Vol. 3 (1-4) , 154-163
- https://doi.org/10.3109/rhe1.1957.3.issue-1-4.19
Abstract
Summary A number of antigens from gram-positive bacteria, especially streptococci, are agglutinated by hemoglobin from human, sheep, horse, rabbit and guinea pig blood. The agglutination factor, to which the globin part of the hemoglobin is ascribed, can be removed by various antigens from hemoglobin solutions. Experiments with various antigen fractions showed a positive reaction between globin and Lancefield's P-substance which is probably one of the nucleoproteins involved in the agglutination. Bacterial agglutination of hemoglobin and globin is a new type of system that can be used for the study of different globin fractions, and serum factors inhibiting this agglutination reaction.Keywords
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