STUDIES ON THE RELATIONSHIP OF PTEROYLGLUTAMIC ACID TO THE GROWTH OF PSITTACOSIS VIRUS (STRAIN 6BC)
Open Access
- 1 September 1948
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 88 (3) , 285-294
- https://doi.org/10.1084/jem.88.3.285
Abstract
P-Aminobenzoic and pteroic acids antagonize the inhibition of the growth of psittacosis virus (strain 6BC) by sulfadiazine in a competitive manner. Pteroylglutamic acid exerts a non-competitive type sulfonamide antagonism. The effects of certain analogues of pteroylglutamic acid and of pteroic acid on the growth of psittacosis virus and its inhibition by sulfadiazine are reported. The implications of these findings with regard to the possible synthesis of pteroylglutamic acid by psittacosis virus and its suggested rôle as an essential factor for growth of this virus are discussed.Keywords
This publication has 6 references indexed in Scilit:
- Antagonism of Sulfadiazine Inhibition of Psittacosis Virus by p-Amino-benzoic and Pteroylglutamic Acids.Experimental Biology and Medicine, 1948
- Acceleration of Pteroylglutamic Acid Deficiency in Mice and Chicks by a Chemical AntagonistExperimental Biology and Medicine, 1947
- THE ANTAGONISM OF SULFONAMIDE INHIBITION OF CERTAIN LACTOBACILLI AND ENTEROCOCCI BY PTEROYLGLUTAMIC ACID AND RELATED COMPOUNDSJournal of Biological Chemistry, 1946
- STUDIES ON THE CHEMOTHERAPY OF VIRUSES IN THE PSITTACOSIS-LYMPHOGRANULOMA VENEREUM GROUP .3. EFFECT OF CERTAIN CHEMOTHERAPEUTIC AGENTS ON THE GROWTH OF PSITTACOSIS VIRUS (6BC-STRAIN) IN TISSUES CULTURES AND EGGS1946
- The Fate of the Virus of Lymphogranuloma Venereum in Infected Mice Receiving Sulfonamide TherapyThe Journal of Infectious Diseases, 1943
- The Effect of Para-Aminobenzoic Acid on the Chemotherapeutic Activity of the Sulfonamides in Lymphogranuloma Venereum and in Duck MalariaJournal of Bacteriology, 1943