Hyperammonemic Encephalopathy and Urinary Obstruction

Abstract
To the Editor: Dr. Drayna and his colleagues point out the possible role of urinary obstruction in the genesis of hyperammonemia (March 26 issue).* We would like to report our experience with a child who presented with a similar condition.An 11-year-old boy with prune-belly syndrome and a history of hydronephrosis, recurrent urinary-tract infection requiring suppression with antibiotics, and mild renal insufficiency (creatinine, 1.5 mg per deciliter [133 μmol per liter]) presented at a local hospital because of five days of vomiting and abdominal pain. Results of physical examination were remarkable for normal vital signs, a markedly distended abdomen, clinical . . .

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