Recurrent intra-cranial granulomata presenting as space-occupying lesions in a patient with common variable immunodeficiency

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Abstract
Summary: A patient with profound panhypogammaglobulinaemia due to common variable immunodeficiency developed two discrete intra-cranial space-occupying lesions, 10 years apart, requiring craniotomy. Histological examination revealed the intra-cranial masses to be granulomata of unknown aetiology on both occasions.