Ultrastructural comparison of Hodgkin's and non‐Hodgkin's lymphomas

Publisher Website
Google Scholar
Abstract
The ultrastructural features of Reed‐Sternberg cells and reactive epithelioid histiocytes from patients with Hodgkin's disease were compared with those of large cell non‐Hodgkin's lymphomas. The cytoplasmic organelles of Reed‐Sternberg cells were dissimilar to those of neoplastic large lymphocytes from follicular centre cell lymphomas, immunoblastic lymphomas, lymphoblastic lymphomas, and mycosis fungoides both in type and distribution. Reed‐Sternberg cells could be distinguished from reactive epithelioid histiocytes; however, the cytoplasmic organization of the Reed‐Sternberg cells bore a closer resemblance to these histiocytes than to the cells of the various large cell non‐Hodgkin's lymphomas.