Antiviral Activity of Flavones and Potentiation by Ascorbate
- 1 July 1988
- journal article
- research article
- Published by Microbiology Society in Journal of General Virology
- Vol. 69 (7) , 1749-1751
- https://doi.org/10.1099/0022-1317-69-7-1749
Abstract
Summary We compared the anti-poliovirus activities of three flavones, quercetin, luteolin and 3-methylquercetin, which differ only at ring position 3. 3-Methylquercetin was the most potent compound. Quercetin exhibited antiviral activity only when protected against oxidative degradation by ascorbate. The antiviral activity of luteolin was comparable to that of ascorbate-stabilized quercetin.Keywords
This publication has 1 reference indexed in Scilit:
- Base-catalysed oxygenolysis of 3-hydroxyflavonesJournal of the Chemical Society, Perkin Transactions 1, 1979