Immune Traffic: A Functional Overview
- 1 June 2003
- journal article
- review article
- Published by Mary Ann Liebert Inc in Lymphatic Research and Biology
- Vol. 1 (3) , 219-234
- https://doi.org/10.1089/153968503768330256
Abstract
The efficient function of the immune system necessitates the complex interaction of antigens, antigen-presenting cells, and cell populations that modulate, regulate and effectuate the immune response. In order to overcome the spatial limitations that are imposed by the constraints of the system, the immune system has evolved a dependence upon the lymphatic vasculature to serve the biological needs of immune trafficking. This review will focus upon useful ex vivo and intact animal models that possess the ability to provide valuable information about leukocyte trafficking.Keywords
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