Mitogen-Stimulated Glutaraldehyde-Fixed Spleen Cells: Ability to Stimulate in the Mixed Lymphocyte Reaction and Generate Effector Cells in Cell-Mediated Lympholysis

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Abstract
Mouse spleen cells treated with glutaraldehyde lose their stimulating ability in the MLR. If the spleen cells are first converted to a blastogenic state by lipopolysaccharide and subsequently fixed with glutaraldehyde, their stimulating capacity is maintained.