Two Radiation-Induced Chromosomal Inversions in Mice ( Mus musculus )
Open Access
- 1 October 1970
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 67 (2) , 961-967
- https://doi.org/10.1073/pnas.67.2.961
Abstract
Whole-body x-irradiation of male mice has produced presumptive paracentric inversions in 15 animals, as evidenced by high frequencies of first meiotic anaphase bridges. Two of the highest frequencies observed have been propagated through several generations and found to behave as dominant genes. Acentric fragments were observed associated with about 10% of the bridges. The first inversion, in linkage group XIII, has been designated In(13)1Rk, and the second, in linkage group XVII, In(17)2Rk. For In(13)1Rk, recombination was reduced between loci inside and outside the inverted segment.Keywords
This publication has 2 references indexed in Scilit:
- An Air-Drying Method for Meiotic Preparations from Mammalian TestesCytogenetic and Genome Research, 1964
- A Colchicine, Hypotonic Citrate, Squash Sequence for Mammalian ChromosomesStain Technology, 1956