Intermittent medication for stable schizophrenic outpatients: an alternative to maintenance medication

Publisher Website
Google Scholar
Abstract
Because of neuroleptics'' potential long-term side effects, a pilot study was conducted of an alternative to maintenance medication for stable schizophrenic outpatients. The doses of 19 patients were gradually reduced to 0 over 8 wk, and medication was then given only when a patient experienced early signs of relapse. The patients attended weekly group therapy and were closely monitored for prodromal signs, especially at times of stress; significant others helped observe the patients. Five patients experienced increased symptoms during the drug washout period and were dropped from the study; of the remaining 14, 10 remained stable on the intermittent medication protocol.

This publication has 14 references indexed in Scilit: