The Effect of Temperature and pH on the Solubility of Quinolone Compounds: Estimation of Heat of Fusion
- 1 January 1994
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 11 (4) , 522-527
- https://doi.org/10.1023/a:1018910431216
Abstract
Although many reports involving fluoroquinolone agents have been published in the past decades, only a few address preformulation studies. In this paper, we describe the effect of temperature and pH...Keywords
This publication has 11 references indexed in Scilit:
- Protonation Equilibria of Quinolone AntibacterialsJournal of Pharmaceutical Sciences, 1990
- Solid and Liquid Heat Capacities of n-Alkyl Para-aminobenzoates Near the Melting PointPharmaceutical Research, 1990
- Fluoroquinolone antimicrobial agentsClinical Microbiology Reviews, 1989
- Fluoronaphthyridines and quinolones as antibacterial agents. 1. Synthesis and structure-activity relationship of new 1-substituted derivativesJournal of Medicinal Chemistry, 1989
- 1-Substituted 7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids. New quantitative structure activity relationships at N1 for the quinolone antibacterialsJournal of Medicinal Chemistry, 1988
- Solubility of Hydrocortisone in Organic and Aqueous Media: Evidence for Regular Solution Behavior in Apolar SolventsJournal of Pharmaceutical Sciences, 1983
- Solubility and Partitioning V: Dependence of Solubility on Melting PointJournal of Pharmaceutical Sciences, 1981
- Solubility and partitioning I: Solubility of nonelectrolytes in waterJournal of Pharmaceutical Sciences, 1980
- General Method for Determining Macrodissociation Constants of Polyprotic, Amphoteric Compounds from Solubility MeasurementsJournal of Pharmaceutical Sciences, 1978
- Importance of Chain Length on Physicochemical and Crystalline Properties of Organic HomologsJournal of Pharmaceutical Sciences, 1972