Current Controversies in Vaccination

Abstract
Vaccination is ranked as one of the 10 greatest public health achievements of the last century and is the number one contribution to decreased global morbidity and mortality.1-3 Pediatric vaccinations have had the most profound impact of any intervention on increasing global child survival, accounting for 3 million pediatric lives saved annually.3 However, even in the 21st century, vaccine-preventable infectious diseases remain important causes of morbidity and mortality in many areas of the world. Globally, tetanus, measles, and pertussis are the main vaccine-preventable causes of death in children; septicemia and influenza-related pneumonia are among the top 10 causes of death in adults and children worldwide, including the United States.4,5