Estimated effectiveness of traveller screening to prevent international spread of 2019 novel coronavirus (2019-nCoV)
Preprint
- 30 January 2020
- preprint
- Published by Cold Spring Harbor Laboratory in medRxiv
Abstract
Traveller screening is being used to limit further global spread of 2019 novel coronavirus (nCoV) following its recent emergence. Here, we project the impact of different travel screening programs given remaining uncertainty around the values of key nCoV life history and epidemiological parameters. Even under best-case assumptions, we estimate that screening will miss more than half of infected travellers. Breaking down the factors leading to screening successes and failures, we find that most cases missed by screening are fundamentally undetectable, because they have not yet developed symptoms and are unaware they were exposed. These findings emphasize the need for measures to track travellers who become ill after being missed by a travel screening program. We make our model available for interactive use so stakeholders can explore scenarios of interest using the most up-to-date information. We hope these findings contribute to evidence-based policy to combat the spread of nCoV, and to prospective planning to mitigate future emerging pathogens.Keywords
All Related Versions
- Published version: eLife, 9.
This publication has 13 references indexed in Scilit:
- Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected PneumoniaNew England Journal of Medicine, 2020
- Clinical features of patients infected with 2019 novel coronavirus in Wuhan, ChinaThe Lancet, 2020
- The incubation period of 2019-nCoV infections among travellers from Wuhan, ChinamedRxiv, 2020
- Pattern of early human-to-human transmission of Wuhan 2019-nCoVbioRxiv, 2020
- A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family clusterPublished by Elsevier ,2020
- Novel coronavirus 2019-nCoV: early estimation of epidemiological parameters and epidemic predictionsmedRxiv, 2020
- Transmission Dynamics of 2019 Novel Coronavirus (2019-nCoV)SSRN Electronic Journal, 2020
- Effectiveness of traveller screening for emerging pathogens is shaped by epidemiology and natural history of infectioneLife, 2015
- Thermal Image Scanning for Influenza Border Screening: Results of an Airport Screening StudyPLOS ONE, 2011
- Entry screening to delay local transmission of 2009 pandemic influenza A (H1N1)BMC Infectious Diseases, 2010