Engineering Microsomal Cytochrome P450 2C5 to Be a Soluble, Monomeric Enzyme
Open Access
- 1 January 2000
- journal article
- Published by Elsevier
- Vol. 275 (4) , 2545-2553
- https://doi.org/10.1074/jbc.275.4.2545
Abstract
No abstract availableKeywords
This publication has 20 references indexed in Scilit:
- Microsomal P450 2C3 Is Expressed as a Soluble Dimer inEscherichia coliFollowing Modifications of Its N-terminusArchives of Biochemistry and Biophysics, 1997
- Construction of a 3D model of cytochrome P450 2B4Protein Engineering, Design and Selection, 1997
- A Three-Dimensional Protein Model for Human Cytochrome P450 2D6 Based on the Crystal Structures of P450 101, P450 102, and P450 108Chemical Research in Toxicology, 1996
- A Model for Human Cytochrome P450 2D6 Based on Homology Modeling and NMR Studies of Substrate BindingBiochemistry, 1996
- Site-Directed Mutagenesis as a Tool for Molecular Modeling of Cytochrome P450 2B1Biochemistry, 1995
- Role of Residue 363 and 206 in Conversion of Cytochrome P450 2B1 from a Steroid 16-Hydroxylase to a 15α-HydroxylaseArchives of Biochemistry and Biophysics, 1994
- SOPM: a self-optimized method for protein secondary structure predictionProtein Engineering, Design and Selection, 1994
- Purification and Characterization of Recombinant-Expressed Cytochrome P450 2C3 from Escherichia coli: 2C3 Encodes the 6β-Hydroxylase Deficient Form of P450-3bArchives of Biochemistry and Biophysics, 1993
- Alteration of mouse cytochrome P450coh substrate specificity by mutation of a single amino-acid residueNature, 1989
- Determination of the membrane topology of the phenobarbital-inducible rat liver cytochrome P-450 isoenzyme PB-4 using site-specific antibodies.The Journal of cell biology, 1987