Physiologic Studies on an Infant in Deep Hypothermia

Abstract
"EVIDENCE accumulated over the past few years -L' indicates that newborn animals are more resistant to asphyxia at reduced than at normal body temperature.1 The rationale for the use of hypothermia in the treatment of asphyxia neonatorum or in similar asphyxial situations depends on van't Hoff's law, which linearly relates the rate of a chemical reaction to temperature.Miller and Marini2 recently described the cardiac activity of an apneic fetus in whom the effects of deep hypothermia were combined with those of perfusion with oxygenated blood. Westin and his associates3 employed similar perfusion in 3 of 6 infants treated by . . .