EFFECT OF CELL DENSITY ON DISAPPEARANCE OF CELL-SURFACE IMMUNOGLOBULINS

  • 1 January 1978
    • journal article
    • research article
    • Vol. C129  (1) , 89-96
Abstract
Mouse macrophages and human peripheral blood lymphocytes with membrane autologous Ig[immunoglobulin]G and mouse thymocytes coated with human IgG showed a strong cell concentration dependence of surface IgG disappearance during incubation at 37.degree. C. Mouse spleen lymphocytes treated with anti-mouse Ig behaved in the same way regarding the disappearance of surface Ig. The redistribution of ligands (cap formation) was not dependent on cell concentration.